В настоящее время получено достаточное количество данных, которые подтверждают важность показателей постпрандиальной глюкозы плазмы[1-7].
О возможностях контроля этого состояния и его вкладе в развитие осложнений сахарного диабета 2 типа рассказал Ашот Мусаелович Мкртумян — д.м.н., проф., зав.кафедрой эндокринологии и диабетологии лечебного факультета и ФПДО МГМСУ им. А.И. Евдокимова.
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1. Sorkin JD, Muller DC, Fleg JL, Andres R. The relation of fasting and 2–h postchallenge plasma glucose concentrations to mortality: data from the Baltimore Longitudinal Study of Aging with a critical review of the literature. Diabetes Care 2005; 28(11):2626–2632.
2. Ohkubo Y, Kishikawa H, Araki E, Miyata T, Isami S, Motoyoshi S et al. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non–insulin–dependent diabetes mellitus: a randomized prospective 6–year study. Diabetes Res Clin Pract 1995; 28(2):103–117.
3. Shiraiwa T, Kaneto H, Miyatsuka T, Kato K, Yamamoto K, Kawashima A et al. Post–prandial hyperglycemia is an important predictor of the incidence of diabetic microangiopathy in Japanese type 2 diabetic patients. Biochem Biophys Res Commun 2005; 336(1):339–345.
4. Levitan EB, Song Y, Ford ES, Liu S. Is nondiabetic hyperglycemia a risk factor for cardiovascular disease? A meta–analysis of prospective studies. Arch Intern Med 2004; 164(19):2147–2155.
5. Hanefeld M, Cagatay M, Petrowitsch T, Neuser D, Petzinna D, Rupp M. Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: meta–analysis of seven long–term studies. Eur Heart J 2004; 25(1):10–16.
6. Woerle HJ, Neumann C, Zschau S, Tenner S, Irsigler A, Schirra J et al. Impact of fasting and postprandial glycemia on overall glycemic control in type 2 diabetes Importance of postprandial glycemia to achieve target HbA1c levels. Diabetes Res Clin Pract 2007.
7. Hanefeld M, Koehler C, Schaper F, Fuecker K, Henkel E, Temelkova–Kurktschiev T. Postprandial plasma glucose is an independent risk factor for increased carotid intima–media thickness in non–diabetic individuals. Atherosclerosis 1999; 144(1):229–235.